Fabian Holenstein
Angestellt, Scientific Technical Leader / Lab Head, Novartis
Basel, Schweiz
Werdegang
Berufserfahrung von Fabian Holenstein
Bis heute 4 Jahre und 10 Monate, seit Sep. 2019
Scientific Technical Leader / Lab Head
Novartis
Lead the large-scale protein production lab (fermentation scale from 2L - 100L) with 3-5 associates to produce antibodies, antigens, tool proteins and therapeutic proteins for Biologics projects from recombinant mammalian cells (transiently or stably transfected) and hybridoma cultures in cost-effective way. Act as Functional Lead for Outsourcing collaboration (eight FTE), being responsible for scientific and technical questions as well as coordination of protein production; perform financial overview
• Act as Functional Lead for Outsourcing collaboration (six FTE), being responsible for scientific and technical questions as well as coordination of protein production; perform financial overview • Conduct lab coordination and act as technical lead for small-/mid-scale mammalian production platform
In addition to previos task, be responsible for work distribution and entry point of 0.1- to 2-liter scale transient expression and purification to support pre-clinical research activities as well as to contribute towards moving Biologics portfolio Forward, drive implementation of new technological solutions and instrumentation, act as a core member on project for customized automated 2-D purification Äkta pure system.
• Work in a laboratory with emphasis on small-/medium-scale production of selected candidates for in vitro and in vivo Targets, independently run 0.1- to 2-liter scale of transient mammalian expression and purification to support pre-clinical research activities as well as to contribute towards moving Biologics portfolio Forward, continuously optimize up- and downstream process of antibody production
4 Monate, Juni 2009 - Sep. 2009
Internship
University of Vermont
3 Jahre und 5 Monate, März 2006 - Juli 2009
Research Associate
Glycart Biotechnology AG (Roche Groupe)
Research associate in the cell line engineering group
Research
3 Jahre und 1 Monat, Aug. 1997 - Aug. 2000
Apprenticeship as pharma biological lab technician
Novartis
Ausbildung von Fabian Holenstein
1 Jahr und 6 Monate, Sep. 2009 - Feb. 2011
Pharmaceutical Biotechnology
University of Applied Sciences Wädenswil
3 Jahre und 7 Monate, Sep. 2002 - März 2006
Biotechnology
University of Applied Science Wädenswil
Sprachen
Deutsch
Muttersprache
Englisch
Fließend
Französisch
Grundlagen