Dr. Dominik Bernhagen

AmbioPharm, headquartered in North Augusta, South Carolina, USA specializing in developing highly efficient manufacturing processes for peptide-based Active Pharmaceutical Ingredients (APIs) at very small to very large scales. In our manufacturing facilities in South Carolina, USA and Shanghai, China, we manufacture New Chemical Entities (NCEs) and generic peptide APIs under cGMP for clients worldwide. Both facilities have been inspected multiple times by the FDA with excellent outcomes.

- Creating and monitoring offers - Scientific and commerical support of customer requests - Active customer support - Contract Negotiation - Business Development, evaluation of new markets, customers and distribution channels - Representation of the company on exhibitions and symposia - Active support in the creation of marketing tools

• Research: Development of integrin-binding peptides o Establishment of a fast and cost-effective assay to screen libraries of peptides for integrin binders o Successful isolation of high affinity integrin αvβ3- and α5β1-binding peptides (manuscript in preparation) • Evaluation of research results, presentation on various conferences and network meetings, writing scientific papers • Fellow of European Union’s project “BIOGEL”: Engineering responsive and biomedical materials for biomedical applications

Synthesis of peptide-functionalized 3D polyisocyanopeptide hydrogels Biocompatibility tests with adipose-derived stem cells

Confocal microscopy studies of cancer cell lines using high affinity, fluorescently-labeled RGD peptides

Synthesis and characterization of peptide-functionalized ELRs and ELR hydrogels

Synthesis of peptide-functionalized PEG hydrogels Biocompatibility tests with mouse fibroblasts

Herstellung von Emulsionen Herstellung von Vesikeln via Phasentransfer Spektroskopische und mikroskopische Charakterisierung

Development of integrin-binding, constrained peptides for application in diagnostics and biomaterials

Polymerchemie, Rhelogie, Organische Synthese, Bioorthogonale Chemie

Kolloid- und Grenzflächenchemie, UV-Vis-Spektroskopie, Fluoreszenzspektroskopie